Ekaterina M. Nestorovich
Room: McCort-Ward G5
Education and Training:
M.S., Electrochemistry, St. Petersburg State University, St. Petersburg, Russia
Ph.D., Electrochemistry, St. Petersburg State University, St. Petersburg, Russia
Post-doctoral research, Biophysics, National Institutes of Health, Bethesda, U.S
Stanford Certified Project Manager, Stanford Center for Professional Development
Biological nanosensors: ion-channel engineering to solve medical problems.
Ekaterina M. Nestorovich earned her Ph.D. in electrochemistry from St. Petersburg State University, Russia under supervision of Prof. Valery Malev. She performed a postdoctoral research in biophysics with Dr. Sergey Bezrukov at the National Institutes of Health. While at the NIH, she mastered the art of ion channel reconstitution into planar lipid bilayers (the models of biological membranes) and modern methods of statistical analysis of ionic currents – powerful tools which allowed her to study kinetic and transport properties of channel-forming proteins at the single-molecule level.
In January 2011, she joined the faculty in the Department of Biology at The Catholic University of America as Assistant Professor of the new Biotechnology program. The direction of her research is best described as medical biotechnology and biophysics.
From the biomedical science perspective, she searches for novel effective approaches to make good use of ion-conducting nanostructures in a variety of medical, chemical, and biotechnological applications. From the biophysical perspective, she pursues a new level of understanding of biological structures through the physical forces that animate them. By learning the physics and chemistry of biological structures’ functioning, Dr. Nestorovich strives to determine how to design new agents that effectively correct the deviant interactions associated with diseases.
Biotechnology Project Management, Rational Drug Design, Biostatistics
Yamini G., Kalu N., and Nestorovich E.M. (2016) Impact of Dendrimer Terminal Group Chemistry on Blockage of the Anthrax Toxin Channel: A Single Molecule Study. Toxins (Basel); 8(11). pii: E337.
Yamini G., Nestorovich E.M. (2016) Multivalent Inhibitors of Channel-Forming Bacterial Toxins. Curr Top Microbiol Immunol. [Epub ahead of print]
Bezrukov S.M., Nestorovich E.M. (2015) Inhibitors of Pore-forming Toxins. 1095-1134. The Comprehensive Sourcebook of Bacterial Protein Toxins.
- Nov 2016 Our laboratory wins two competitive Biophysical Society travel awards to attend 2017 Biophysical Society Annual Meeting in New Orleans, LA: an Education Travel Award to Goli Yamini and a Professional Opportunities for Women Award to Katia Nestorovich. Congratulations!
- Apr 2016 Sanaz Momben Abolfath and Nnanya Kalu volunteer at the Biomolecular Dome hosted by the Biophysical Society Public Affair Committee at the USA Science and Engineering Festival in Washington DC. This free event was attended by thousands of people of all ages and background (and many high school kids!) who are interested in learning more about science.
- Apr. 2016 Nnanya Kalu, wins CUA Research Day student award for his poster "Lipid Composition Regulates Anthrax Toxin Uptake". Congratulations!
- Feb. 2016. Nestorovich's lab presents two posters at the Biophysical Society Meeting in LA.
- Nov. 2015. Nnanya Kalu wins a competitive Biophysical Society Education Commitee Travel Award to attend the 2016 Biophysical Society Annual Meeting in Los Angeles, CA.
- Feb. 2015: Nestorovich's lab presents two posters at the Biophysical Society Meeting in Baltimore.
- Sept. 2014: Nnanya Kalu receives The Roland M. Nardone Award for Graduate Teaching Excellence. Congratulations!
- Sept. 2014: Nnanya Kalu gave a talk at Biology Graduate Student Symposium.
- Aug. 2014: Ekaterina Nestorovich has received an Academic Research Enhancement Award (R15) from the NIAID to investigate universal polyvalent inhibitors of binary bacterial toxins.